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The Apheresis Center

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  • Treatments
    • COMBINATION THERAPY
    • Clinical Nutrition
    • H.E.L.P. Apheresis
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    • Immunoadsorption
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    • IVIG and mABs Therapy
    • Nutraceutical Therapy
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    • Anticoagulation Therapy
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    • HBOT - Hyperbaric Oxygen
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COMBINATION THERAPY

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The Cyprus Protocol - Multimodal Combination Therapy for Long COVID, Post-Vac and Chronic Illnesses

In the field of HIV and cancer, combination therapy is one of the most successful forms of treatment - often it is the gold standard in the specific field. 


Together with contributors all around the world and through our clinical experience combined with patient-led research we have developed the first multimodal Combination Therapy protocol for Long COVID, Post Vac Syndrome and Chronic Illnesses.


 We named it after it's place of origin: 

'The Cyprus Protocol'


Below you find a dynamic list of the protocol's elements and a treatment schedule example.

Combination Therapy

The Cyprus Protocol Elements

Click on the each element of the Cyprus Protocol for more details

For every patient the protocol needs to be individualised.


With the new diagnostic tools (molecular spike diagnostics, autoantibody panels et cetera) we are now able to apply targeted treatments with higher precision.


Independent of the treatment a patient is undergoing - without adapted nutrition for the three treatment phases pre-treatment, on-treatment and post-treatment, the achievable results differ.

This is why we base our Combination Therapy on individual and personalized nutrition plans for every patient, based on the results of blood panel test and food intolerance test that show IgG reactions to 287 foods (vegetables, fish & seafood, fruits, spices, nuts, legumes, meat, egg & milk, cereals & seeds, nuts, coffee & tea and novel foods). 

Our Clinical Nutritionist Chryso Zorbas will hold your hand nutritionally from day one and guide you along the therapy with a personalized diet plan that will enhance your recovery process. Needless to say that our Health Coaching (see below) is a perfect match and goes hand in hand with our Clinical Nutrition Supervision.


Learn more about Clinical Nutrition Supervision here


Chronic Illness is very complex - having an expert patient turned professional Health Coach by your side throughout your whole journey offers priceless knowlege and guidance.

Our Health Coach Tanja Walser will coach you from day one and guide you along the therapy with a personalized coaching plan that will include all the dos and don'ts and give you a headstart despite brainfog, anxiety or other symptoms you are battling with.


Learn more about Health Coaching here


Our most effective treatments to date: At the core of our multimodal Combination Therapy are several forms of Therapeutic Apheresis' - special blood purifications by precipitation/adsorption/filtration procedures. They serve to treat microcirculation / blood flow issues (microclots are removed, blood flow increased) and removes pathogenic or disease-sustaining proteins as well as protein-bound substances and autoantibodies from the blood. Amongst other substances environmental toxins, inflammation proteins, viral spike protein, cholesterol + autoantibodies are removed


Learn more about H.E.L.P. Apheresis 

Learn more about Inuspheresis®  

Learn more about Immunoadsorption 

In some cases H.E.L.P. Apheresis will be combined with TPPE - Therapeutic Partial Plasma Exchange 


The Heckel HT3000 whole-body hyperthermia system allows a targeted  increase in the body’s core temperature, ranging from a mild to high fever. Whole-body hyperthermia not only addresses symptoms, but also aims to re-establish improved regulatory control within the entire organism. The Heckel whole-body hyperthermia systems are a meaningful  contribution to treatments of a wide range of illnesses and conditions – ranging from health promotion, to alleviating pain and supportive treatment in chronic conditions and cancer. In Long Covid and Post Vac the freeing of receptors and breaking up of pathogenic proteins are further desired effects.


Long Covid and many other Chronic Illnesses are at their root an endothelitis/vasculitis with severe inflammation, combined with hypercoagulation and often viral persistence. Autoimmunity components can be involved too. 

IV treatments work directly where needed the most: in the blood vessels in the desired concentration.


IV/Intravenous therapies that are used in our Long COVID and Chronic Illnesses Combination Therapy are:


- IV Vitamin C (Reducing inflammation)

- IV Glutathione (Antioxidant)

- IV Multivitamin Protocol (Balancing deficiencies)

- IV NAD+ (Metabolism/mitochondria benefits)

- IV Alpha Lipoic Acid (Metabolism/nerve pain reduction)

- IV Zinc (Reducing inflammation, speeding up recovery)

- IV Magnesium (Electrolyte reducing fatigue and anxiety)

- IV NAC (Reduces brainfog/relieves respiratory discomfort)

- IV Taurin (Is Cytoprotective (cell protective) and detoxyfying)

- IV Arginine (Increases elasticity of blood vessels and increases blood flow)

- IV Lysine (Increases cell healing and wound healing)

- Other IVs: Iron, Selenium, Amino Acids, Minerals and more


Peptide Therapy:


Peptide therapy offers a groundbreaking approach to restoring  balance and vitality for individuals struggling with long COVID,  post-vaccine syndrome, and chronic illnesses. Peptides are short chains  of amino acids that act as signaling molecules in the body, promoting  tissue repair, immune modulation, and cellular rejuvenation. By  targeting underlying dysfunctions such as inflammation, impaired  immunity, and mitochondrial damage, peptide therapy can accelerate  recovery, enhance energy, and support overall wellness. Tailored to each  patient’s unique needs, this therapy provides a safe and effective way  to improve quality of life, fostering the body’s natural ability to heal  and thrive.  


Find more information on our IV Therapy and Peptide Therapy click here for iv therapy and peptide therapy


Chelation Therapy:


Chelation therapy is a medical intervention characterized by the administration of chelating agents, substances with a high affinity for certain metal ions, to facilitate the removal of heavy metals and minerals from the body. 


Find more information on Chelation Therapy here




Medication and supplement protocols increase H.E.L.P. Apheresis results further and can be used to treat patients symptom-specific. The protocols include Antiviral Protocols and Anticoagulation Protocols.


Symptoms the medication protocols focus on are:


- Viral persistence

- Persisting hyper coagulation

- MCAS (mastcell activation syndrome), often combined with gastroparesis

- Endothelial damage, often combined with hypercholesterolaemia 

- Neuro inflammation/brain inflammation

- Fatigue, PEM often combined with mitochondrial dysfunction

- Insomnia 

- Induced anxiety/paranoia/depression 

- Reactivated viruses

- Others


Find more information on Antiviral Therapy and Anticoagulation Therapy


Anxiety, Depression, PTSD, Chronic Pain and Fatigue Therapy for Long Covid and Chronic Illness

Are you or a loved one struggling with the lingering effects of Long Covid or battling the relentless challenges of chronic illness? At the Apheresis Center we understand the toll these conditions can take on both your physical and mental well-being. That's why we offer revolutionary approaches to treatment.


Find more about Depression & Anxiety Therapy here


Colon Hydrotherapy, also known as colonic irrigation, constitutes an internal cleansing procedure designed to rid the colon of deleterious waste materials. This therapeutic intervention serves as a rapid and highly efficient means of detoxification for the body. The mild internal hydration expeditiously eliminates pathogenic toxins by leveraging the natural peristaltic movements, further facilitated by abdominal massage. Notably, this process has implications for individuals with symptoms that present similar to Mast Cell Activation Syndrome (MCAS), as it influence the systemic responses associated with this symptoms often triggered by Long Covid, Post Vac or other Chronic Illnesses.


Our Medical Team has designed a MCAS treatment package which is tailored to each patient individually


  • MCAS Blood Test (CCL2, IL-6, IL-8, IL-31, IL-33, TNF-alpha, Tryptase)
  • Nutrition Plan
  • 3x Colon Hydrotherapy, ozonated treatment
  • 3x Leaky Gut IV (L-Lysin, Taurin, L-Alanyl-Glutamin, Glycin, Cholinchlorid, Magnesiumchlorid, Kaliumchlorid 
  • MCAS Medication Plan including Nutraceuticals and Nanozeolites 


Find more information on Colon Hydrotherapy and MCAS Treatment here


The application of Intravenous Immunoglobulin (IVIG, if subcutaneously administered also called SCIG)) and monoclonal antibodies (mABs) like Evusheld or Xevudy (Sotrovimab) represents a new area in treating Long Covid, Post Vac and Chronic Illnesses. These conditions involve complex immune dysregulation and inflammatory responses. IVIG is a concentrated preparation of immunoglobulins derived from pooled human plasma.

Monoclonal antibodies, designed to target specific components of the immune response, present another avenue for intervention. Both IVIG and mABs are being investigated for their potential to restore immune homeostasis.

The current official indications include symptoms present in chronic illness and many post-viral conditions: Myo- and Pericarditis, Small Fiber Neuropathy but also acute/severe conditions like Sepsis.


Find more about IVIG and mABs Therapy here


Our Nutraceutical treatment strategy for the detoxification from viral spike protein involves the following 4-step process:


  1. The first step is preventing reinfection by blocking the receptors  on host cells, which the virus and viral spike protein use to gain  entry. 
  2. The second step is to help restore autophagy processes, which are  the body’s natural way of cleaning out damaged cells and regenerating  new ones. 
  3. The third step aids in liberating viruses and viral spike proteins by selectively targeting infected or transfected cells. 
  4. The fourth step facilitates the sequestration of viral spike  protein and virus, effectively removing them. The most efficient way to  do this is H.E.L.P. Apheresis and where that is not possible, the use of  Algerol is indicated.

This  comprehensive approach aims to remove the spike protein from the body  safely while also enhancing the immune system’s ability to prevent  further infections.


At the end of our therapy course we add a 3-6 months NAC Augmented protocol.


Find more about Nutraceutical Therapy here


For specific symptoms and subgroups after H.E.L.P. Apheresis treatment these treatments can speed up and enforce the recovery process. (Note: HBOT is only administered after H.E.L.P. Apheresis therapy. Ozone-EBOO is only administered after H.E.L.P. Apheresis and only in special cases) 


Find more information on Hyperbaric Oxygen Treatment here and Cryotherapy here


Mitochondrial therapy, also known as metabolic correction, is an emerging approach in the management of Long Covid and chronic illnesses characterized by fatigue. This therapy aims to enhance mitochondrial function, which is often impaired in these conditions, by providing specific nutrients and cofactors that support cellular energy production. Key substances used in mitochondrial therapy include NAC (N-Acetyl L-Cysteine), L-Serine, L-Carnitine, Nicotinamide Riboside (NR), L-Choline, NT Factor, and NADH. These compounds work synergistically to replenish depleted cellular antioxidants, enhance mitochondrial biogenesis, improve fatty acid metabolism, and restore ATP production, ultimately helping to alleviate fatigue and improve overall cellular health in individuals suffering from prolonged symptoms of Long Covid and other chronic fatigue-related conditions.


Find more about Mitochondrial Therapy here


Many of our last year's patients had to come back to us for another course of H.E.L.P. Apheresis and Combination Therapy treatment, because they reinfected with Covid and were thrown back to experiencing Long Covid symptoms. This is why we started giving out 'Early Treatment packages' which avoid exactly that. Our prescribing doctors will supply you with everything needed to get through your next reinfection without risking to worsen again. 


Treatment Schedule Example

Visualisation of treatment options of the Cyprus Protocol

In the below PDF you find a visualisation of available treatments (this is solely for the purpose of demonstrating available options - this NOT a real life case/treatment schedule)


Recommendation: Download and zoom in for details.

Download PDF

Scientific Sources and Studies on Therapeutic Apheresis for Long Covid/Post Vac & other conditions

H.E.L.P. Apheresis


  • Gavin Infectious Diseases Diagnosis & Treatment 
  • Researchgate
  • Springer
  • Frontiers
  • Therapheutic Apheresis and Dialysis
  • Journal of Thrombosis and Haemostasis
  • Springer Nature 
  • The American Journal of Medicine
  • PubMedCentral
  • Science


A collection of sources which have published success rates can be found at the Long Covid Apheresis Community (LCA Community): https://lcacommunity.org/research


The results published by the LCA Community have been confirmed at the ISFA2023:

ISFA 2023 (International Society for Apheresis World Conference)


Inuspheresis


  • Nature
  • Genomic Press
  • Pubmed
  • Thieme Connect
  • Pubmed



Science 2024 - new study looking at the relation between microclots and immune damage in Long Covid:


Quote: '...coagulation in Long Covid is indicated by the detection of circulating fibrinolysis-resistant microclots that are enriched in vWF, C7, acute-phase serum amyloid proteins, and fibrin, proteins identified in the proteomics screen by Cervia-Hasler et al. as contributors to Long Covid.'


Full study: https://www.science.org/doi/10.1126/science.adn1077


In simpler terms, this study investigates the reasons behind persistent symptoms in some people after recovering from COVID-19, a condition known as Long Covid. The researchers found that Long Covid patients have ongoing activation of the immune system, specifically the complement system, which leads to inflammation and blood clot formation. Unlike during acute COVID-19, where the liver plays a major role in immune responses, in Long Covid, the inflammation seems to be more localized, involving tissues and immune cells. The study suggests that this persistent immune activation, particularly in the complement system, contributes to the symptoms experienced by Long Covid patients.


The researchers identified specific proteins, such as pentraxin 3 and complement components, that are associated with Long Covid. The complement system, when uncontrolled, can cause damage to cells and blood vessels. In Long Covid patients, there is evidence of excessive complement activation, leading to inflammation and microclot formation. This ongoing inflammatory state, even in the absence of widespread blood clotting, can explain the lingering symptoms observed in Long Covid, such as fatigue and cognitive issues.


Additionally, the study found imbalances in factors related to blood clotting, suggesting a potential mechanism for thromboinflammation in Long Covid. While the exact reasons for the persistent immune activation and clotting in Long Covid are not fully understood, the study indicates that targeting specific components of the immune and clotting systems could be a potential avenue for treatment in Long Covid. 


H.E.L.P. Apheresis and Inuspheresis®  address most if not all of the above. Microclots, Hypercoagulation, Inflammation, Pathogens to list just a few modes of action of H.E.L.P. Apheresis and Inuspheresis® . The rest can be addressed by other elements of the multimodal Combination Therapy of 'The Cyprus Protocol'.


You will find extensive information on our blog post about different types of Apheresis and which type is suitable for which purpose HERE

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E-mail us info@apheresiscenter.eu | Call us +357 24257400

Our Apheresis Center and H.E.L.P. Apheresis on TV

ITV News, BBC News, France 2 and WDR TV. Excerpts from some of the reports about our Apheresis Center and H.E.L.P. Apheresis for Post/Long Covid, Post Vac Syndrome and Chronic Illness.

Testimonials

Jeremy Smith, Long Covid, United States

'I had 4 Help Apheresis treatments last year in Germany. They brought me back to 80% of my former capacity. 

The Apheresis Center is a totally different experience and I am super happy I chose Cyprus. It is very different from Germany. The doctors, nurses and the whole team are doing everything to bring me back to my full capacity, their knowledge about Long Covid and the individually adapted treatment is great - a real concierge medicine experience! I missed home last year in Germany - here in Cyprus not a single day, we even extended our stay and will come back next year for holidays!'

You can read and watch Jeremy's full story here: Full Video

Katrina Krulla, Long Covid, United States

'I have had some amazing results with H.E.L.P. Apheresis for my Long Covid - my 6th treatment got me back to feeling 75% to 90% recovered. Larnaca was truly an amazing place for recovery. Also the great community for support that formed with others getting treatment was so wonderful. It was so nice to have a team of people helping you that "got it" and believed you in addition to being with others suffering the same life changing illness.'

Patricia Price, ME/CFS, UK

Landen Williams, Long Covid, US

Landen Williams, Long Covid, US

Patricia has been suffering from severe MECFS since 2015:

'My Help Apheresis treatment improved my ME by 80%. Help Apheresis took me from being mostly bed bound 23 hours a day - I could not be upright without my heart jumping to 170 beats per minute, even higher if I tried to have a shower - to being able to be upright and be mobile almost every day. It changed my life! I can now manage my own life again. I can go outside again and I was able to gain weight and can now eat three solid meals a day again!


You can watch Patricia's full story here: Full Video

Landen Williams, Long Covid, US

Landen Williams, Long Covid, US

Landen Williams, Long Covid, US

Landen was struggling with breathing, anxiety, brain fog and other symptoms before we treated him with H.E.L.P. Apheresis. Several months after the treatment he is now back to 70% of his former self, some fatigue and PEM are the last symptoms partly persisting. He is tackling them with Combination Therapy. The above video is a short version/excerpt of his appearance on 1819 News (Source: 1819news)

For more testimonials click here

Combination Therapy and H.E.L.P. Apheresis do not achieve the same results in the same time frame for different patients. From our clinical experience we have seen similar success rates as presented on the ISFA 2023 (World Conference of the International Society for Apheresis) - 80% success rate with results varying from smaller improvements to being fully curative. The majority of patients saw a significant improvement. Long Covid, Post Vac and CI are umbrella terms with different subsets - no patient presents the exact same symptoms set.


The time frame in which patients see results also vastly differs - from first treatment to several months. 

ARTE TV Documentary 'Long Covid - Healing in Cyprus'

ARTE TV Documentary 'Long Covid - Healing in Cyprus' about our Apheresis Center

In fall 2023, a team of journalists from European TV channel ARTE TV accompanied three of our Long Covid and Post Vac Syndrom patients and interviewed them and our team at the Apheresis Center. Below you find the link to watch short excerpts of the documentary which are also easy to watch for patients with cognitive dysfunction, brainfog and related migraines. The documentary aired in June 2024. 

Click here to watch

Patient Reviews

Apheresis Center, H.E.L.P. Apheresis & Combination Therapy

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Apheresis Center

49 Eleftherias Avenue, Aradippou

7102 Larnaca, Cyprus 


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phone +357 24257400 


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email info@apheresiscenter.eu 



OPENING HOURS:

Monday - Friday 09.00 AM - 05.00 PM (Time Zone Nicosia/Athens)

Closed on Cyprus Public Holidays (on bank holidays only)


We speak German, English, Greek, Hebrew, Spanish, Croatian and Russian.


Apheresis Center is a brand of Raegal Management Limited



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