Whole Body Hyperthermia

Hyperthermia enabled by research and modern technology

At the Apheresis Center we combine apheresis and hyperthermia treatments to increase treatment results. The effects include the freeing of receptors and breaking up of proteins at fever temperature.

The Heckel HT3000 whole-body hyperthermia system allows a targeted increase in the body’s core temperature, ranging from a mild to high fever. Whole-body hyperthermia not only addresses symptoms, but also aims to re-establish improved regulatory control within the entire organism. The Heckel whole-body hyperthermia systems are a meaningful contribution to treatments of a wide range of illnesses and conditions – ranging from health promotion, to alleviating pain and supportive treatment in chronic conditions and cancer.

Range of indications:

Whole-body hyperthermia is a supporting therapy module that can be combined synergistically with other therapies to treat indications including:

• Major depression ( Study: https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2521478 )
• Cancer (additive, as immunostimulation and to boost the effectiveness of standard therapies)
• Chronic infections (e.g., Lyme disease) and chronic post-infection-syndroms (e.g., Post-Covid and Post-Vac, post-mononucleosis) 
• Fibromyalgia, non-articular rheumatism, muscular tension
• Degenerative diseases, arthrosis
• Chronic inflammation: broncho-pulmonary (e.g. asthma, chronic bronchitis), intestinal (e.g. ulcerative colitis, Crohn’s disease), urogenital (e.g. chronic prostatitis), dermatological (e.g. neurodermatitis, psoriasis)

Links to current research:

David M. Smadja, M. Marc Abreu:

  Hyperthermia and targeting heat shock proteins: innovative approaches for neurodegenerative disorders and Long COVID

https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2025.1475376/full

           Heckel-Reusser S: Whole-Body Hyperthermia (WBH): Historical Aspects, Current Use, and Future Perspectives. OPEN ACCESS https://link.springer.com/content/pdf/10.1007%2F978-3-030-92880-3_11  

Zschaeck S, Beck M: Whole-Body Hyperthermia in Oncology: Renaissance in the Immunotherapy Era? OPEN ACCESS https://link.springer.com/content/pdf/10.1007%2F978-3-030-92880-3_8  

Knobel A, Hanusch K, Auen N, Rübener F, Fischer S, Borzim C, Heinz A, Schäfer M: Whole-Body Hyperthermia (WBH) in  Psychiatry OPEN ACCESS https://link.springer.com/content/pdf/10.1007%2F978-3-030-92880-3_12  In: Water-filtered Infrared A (wIRA) Irradiation: From Research to Clinical Settings [Internet]. Cham (CH): Springer; 2022. Chapter 8, 11,

The diagnosis and treatment of post-COVID and post-vaccine syndrome is one of the major challenges facing medicine today. Fever-range whole-body hyperthermia (FR-WBH) has emerged as an important treatment module in various hospitals and clinics. 

Two publications on this topic have been published this year:

[GERMAN] Matthes H: Diagnostik und Therapie bei Post-COVID-19 und Post-Vaccination-Syndrom - Ein Erfahrungsbericht aus dem Krankenhaus Havelhöhe Berlin. Deutsche Zeitschrift für Akupunktur|   Ausgabe 1/2025. OPEN ACCESS / ENGLISH VERSION AI translated

At the apheresis center there, whole-body hyperthermia is used particularly for the treatment   of exosomal spicopathy and to enhance immunoadsorption apheresis in severe cases with GPCR autoantibody findings.

Vagedes J et al: Whole-body hyperthermia as part of a multimodal treatment for patients with   post-covid syndrome – a case series. Int J Hyperthermia, 42(1). OPEN ACCESS 

A retrospective analysis of 46 patients treated with a multimodal therapy concept including   fever-range whole-body hyperthermia at the Paracelsuskrankenhaus Bad Liebenzell showed significant improvements in quality of life. Data were collected using the validated FACIT-F and FIS-D questionnaires at admission, discharge, and 4 weeks after discharge.