Why You Still Feel Sick: The Hidden Biology of Long COVID

Author: George Kyriacou

You’re not just tired. You’re fighting something deeper.

If you’ve been told that your blood work looks normal, or your symptoms are just anxiety — you’re not alone. Thousands of people around the world are living with persistent symptoms that standard tests can’t explain.

Recent research has uncovered powerful insights: the root causes of Long COVID are biological — not psychological — and they’re finally being understood.

What’s Really Causing Your Symptoms?

1. Microclots: Blockages in Your Bloodstream

Tiny clots form in the blood of many Long COVID patients, blocking oxygen and nutrition delivery to vital organs including the nerves and brain. These microclots can starve your tissues and cause symptoms like:

  • Brain fog
  • Fatigue
  • Shortness of breath
  • Muscle pain

🩸 Microclots are not detected by standard tests — they require specialized analysis. 

2. Endothelial Damage: The Lining of Your Blood Vessels

The virus can damage the inner lining of your blood vessels, reducing their flexibility and responsiveness. This contributes to poor blood flow and inflammation.

3. Immune Dysfunction: When the System Stays Stuck

Many patients develop immune system imbalances — including the persistence of autoantibodies like GPCR AABs, which interfere with nerve signaling and cause symptoms of dysautonomia, like:

  • Dizziness upon standing
  • Heart palpitations
  • GI discomfort or MCAS (Mast cell activation syndrome)
  • Exercise intolerance

Visual Breakdown 

  • Microclots → Tissue oxygen starvation and systemic hyperinflammation
  • Endothelial dysfunction → Circulatory issues
  • Autoantibodies → Nervous system disruption and autoimmune tendencies

Why Isn’t My Doctor Finding Anything Wrong?

Because most standard tests — like basic blood work or heart scans — aren’t designed to detect microvascular damage or immune dysregulation.

That’s why we use:

  • Advanced Diagnostics for Microclots
  • GPCR Autoantibody Screening
  • Spike Protein Persistence Tests in Serum, Exosomes, Immune Cells
  • Advanced Mitochondrial Tests
  • Advanced Clinical Evaluation

We don’t guess. We test and treat based on data.

Patient Testimonials

“I saw several doctors before coming to the Apheresis Center. They told me it was just stress. After my microclot test came back positive, I finally had proof — and a plan.”
— Robyn, UK

“Apheresis changed everything. After six sessions, my brain fog cleared and I could finally work without feeling like I’d collapse.”
— Mia, Norway

How We Treat the Root Cause — Not Just Symptoms

Our combination therapy approach combines:

Also see: Why Long COVID Should Be Treated Like a Chronic Condition

Take the First Step

We specialize in treating complex, misunderstood conditions. If you’re still suffering months after your infection or vaccine — don’t wait.

👉 Take the Microclot Test
👉 Book a Free Consultation

Frequently Asked Questions (FAQs)

What are the symptoms of microclots in Long COVID?
Fatigue, brain fog, muscle pain, and shortness of breath are common. They result from impaired blood flow due to clotting in small vessels.

Can Long COVID cause autonomic dysfunction?
Yes. Autoantibodies like GPCR AABs can disrupt autonomic nervous system signaling, causing dizziness, rapid heartbeat, and temperature regulation issues.

How is microclot testing done?
We perform a specialized blood analysis by flow cytometry (Biocode method), designed to detect microclot presence.

Is apheresis safe?
Yes. H.E.L.P. Apheresis, Inuspheresis and Immunoadsorption are well-tolerated and used in top European centers. We perform a pre-treatment screening to ensure safety.

What makes your clinic different?
We combine data-driven diagnostics, precision apheresis, and supportive therapies under one roof — in a clinic purpose-built for chronic immune dysfunction.

Still unsure? We’re here to listen. Chat to Us on WhatsApp — no obligation.